Standard opiate immunoassays test for opium alkaloids and or metabolites incl morphine codeine Semisynthetic opioids may or may not be detected and synthetic opioids will not be detected by opiate immunoassay assays specific for these drugs may be request

By rray, 4 April, 2024
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<sup>1</sup> Raouf M, et al. A Practical Guide to Urine Drug Monitoring. <i>Fed Pract.</i> 2018 Apr;35(4):38-44. <a href=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368048/pdf/fp-35-04-38.pdf><u>Free, full-text PDF</u></a>
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<sup>2</sup> Moeller KE, et al. Clinical Interpretation of Urine Drug Tests: What Clinicians Need to Know About Urine Drug Screens. <i>Mayo Clin Proc.</i> 2017 May;92(5):774-796. <a href=https://www.mayoclinicproceedings.org/action/showPdf?pii=S0025-6196%2816%2930825-4><u>Free, full-text PDF</u></a>
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<sup>3</sup> Argoff CE, et al. Rational Urine Drug Monitoring in Patients Receiving Opioids for Chronic Pain: Consensus Recommendations. <i>Pain Med.</i> 2018 Jan 1;19(1):97-117. <a href=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516588/pdf/pnx285.pdf><u>Free, full-text PDF</u></a>
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<sup>4</sup> Substance Abuse and Mental Health Services Administration. <i>Medications for Opioid Use Disorder.</i> Treatment Improvement Protocol (TIP) Series 63 Publication No. PEP21-02-01-002. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2021. <a href=https://store.samhsa.gov/sites/default/files/pep21-02-01-002.pdf><u>Free, full-text PDF</u></a>
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<sup>5</sup> Jarvis M, et al. Appropriate Use of Drug Testing in Clinical Addiction Medicine. <i>J Addict Med.</i> 2017 May/Jun;11(3):163-173. <a href=https://downloads.asam.org/sitefinity-production-blobs/docs/default-source/guidelines/the-asam-appropriate-use-of-drug-testing-in-clinical-addiction-medicine-full-document.pdf?sfvrsn=700a7bc2_0><u>Free, full-text PDF</u></a>
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<sup>6</sup> Kapur BM, Aleksa K. What the lab can and cannot do: clinical interpretation of drug testing results. <i>Crit Rev Clin Lab Sci.</i> 2020 Dec;57(8):548-585. <a href=https://www.tandfonline.com/doi/epdf/10.1080/10408363.2020.1774493?needAccess=true><u>Free, full-text ePDF</u></a>
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Standard opiate immunoassays test for opium alkaloids and/or metabolites, incl. morphine/codeine. Semisynthetic opioids may or may not be detected, and synthetic opioids will not be detected by opiate immunoassay; assays specific for these drugs may be requested.<sup>1</sup>