If stable w marked hypercapnia consider NPPV NPPV may improve hospital free survival in select pts post recent hospitalization esp if daytime PaCO2 53 mmHg B Long term NPPV beneficial in pts w severe chronic hypercapnia and hx of hospitalization for acute

<b>If stable w/ marked hypercapnia, consider NPPV.</b> NPPV may improve hospital-free survival in select pts post-recent hospitalization, esp. if daytime PaCO₂ >53 mmHg [B]. Long-term NPPV beneficial in pts w/ severe chronic hypercapnia and hx of hospitalization for acute resp failure [B]. If COPD+OSA, CPAP has clear benefits.