A healthy 40-yo woman on no meds originally from sub-Saharan Africa c/o 5 mo of itchy papules around her mouth. Exam showed a cluster of pearly papules. What is it?
Milia
Acne vulgaris
Folliculitis
Herpes simplex
Molluscum contagiosum
You are correct. Molluscum lesions are small, benign, pearly papules caused by a poxvirus. Molluscum is most common on the face and trunk in children and in the genital area in sexually active adults. Molluscum is uncommon on the face of healthy adults and should prompt investigation for immunocompromise, including CBC and HIV serology. This patient was found to be HIV positive and was treated with HAART and topical imiquimod. Molluscum infection is usually self-limited, and treatment is not required in otherwise healthy patients.
A young woman presented with lesions on her lips, tongue, and oral mucosa. Finger lesions and low-grade fever began a few days after the oral lesions. What is it?
Coxsackie virus
Impetigo
Herpes simplex
Kawasaki disease
Behcet's disease
You are correct. Swabs from the lesions tested positive for HSV1 by PCR. Occasionally, as in this case, autoinoculation can cause lesions at multiple sites. HSV1 is usually uncomplicated in immunocompetent hosts. Lesions last 10 to 14 days. Oral antiviral treatment shortens the duration and reduces symptoms.
A 54-yo man with mild HTN on no meds c/o of dysarthria, trouble with swallowing and moving his tongue. Neuro exam was normal except for left-side tongue deviation. Blood work excluded infection or immune disorders. An MRI was performed. What is it?
Multiple sclerosis
Complicated migraine
Subarachnoid hemorrhage
Carotid artery dissection
Acute cerebral vascular occlusion
You are correct. MRI showed carotid artery dissection, without abnormal signal in the hypoglossal nerve. Isolated hypoglossal nerve palsy is associated with lesions of the peripheral segment rather than at the brainstem origin. The hypoglossal nerve passes between the carotid artery and the internal jugular vein. In one series, >5% of patients with internal carotid artery dissection presented with isolated hypoglossal nerve involvement. This patient was treated with antihypertensive and antiplatelet medication. Symptoms improved by 3 weeks after admission.
(BMJ) - A 19-yo man with no PMHx had a chest tube placed for a large spontaneous pneumothorax. Symptoms initially improved, but soon he began coughing up frothy, clear, yellow, sputum and developed respiratory distress. X-ray was repeated. What is the diagnosis?
Reexpansion pulmonary edema
Chest tube malfunction
Lung abscess
Atypical pneumonia
Pulmonary hemorrhage
You are correct. Reexpansion pulmonary edema is a complication of drainage of pleural effusions and pneumothoraces. Large volume, clear (not bloody) sputum is common. X-ray reveals unilateral diffuse airspace opacification of the reinflated lung with the chest tube in place. Management is supportive. The use of diuretics for the condition is controversial. This patient rapidly improved with high-flow O2, morphine, and furosemide; he was discharged 2 days later.
(BMJ) - A 74-yo man with no past medical Hx c/o pain and blisters on his right hand several hours after playing hockey. There was no trauma to his hands. He had no fever or other symptoms. What is the diagnosis?
Allergic reaction
Flexor tenosynovitis
Herpes zoster
Blistering distal dactylitis
Frostbite
You are correct. Blistering distal dactylitis is a superficial bacterial infection of the anterior fat pad, typically caused by gram-positive organisms. It presents with large blisters or bullae affecting multiple fingers. His clinicians hypothesized that lacing up hockey skates may have caused superficial microtrauma to the hands, predisposing to potential infection. Moist, infrequently washed hockey equipment may have harbored infectious organisms. He improved after 10 days of oral cephalexin, blister debridement via lateral puncture, and silver sulfadiazine dressings.
(BMJ) - A 40-yo man c/o nasal blockage x 11 yrs, anosmia, and “something coming out of my nose.” Hx includes hay fever and aspirin intolerance. Exam revealed bilateral glistening fleshy structures in his nose, left worse than right. What is the diagnosis?
Septal hematoma
Deviated septum
Nasal foreign body
Rhabdomyosarcoma
Gross nasal polyps
You are correct. Nasal polyps, a benign inflammation of the nasal sinus mucosa, are a common cause of nasal obstruction and often result from chronic rhinosinusitis. Initial treatment is with topical steroids. This patient did not respond to steroids; nasal polypectomy was performed.